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Convenient Preparation of Long-Chain Dialkyl Phosphates: Synthesis of Dialkyl Phosphates

R. Alan Aitken*, Chris J. Collett, Shaun T. E. Mesher

*EaStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK, Email:

R. A. Aitken, C. J. Colett, S. T. E. Mesher, Synthesis, 2012, 44, 2515-2518.

DOI: 10.1055/s-0031-1290823


Reaction of phosphorus oxychloride with a primary alcohol and triethylamine in toluene, followed by filtration and treatment with steam, gives dialkyl phosphates in good yield and essentially free from trialkyl phosphate impurities.

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Key Words

dialkyl phosphates, esterification, hydrolysis, hydraulic fracturing, enhanced oil recovery

ID: J66-Y2012-2500