Organic Chemistry Portal

Abstracts

Search:

Room Temperature, Palladium-Mediated P-Arylation of Secondary Phosphine Oxides

Aaron J. Bloomfield and Seth B. Herzon*

*Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States, Email: seth.herzonyale.edu

A. J. Bloomfield, S. B. Herzon, Org. Lett., 2012, 14, 4370-4373.

DOI: 10.1021/ol301831k


Abstract

A broad range of aryl iodides are efficiently coupled with secondary phosphine oxides using low loadings of a catalyst formed in situ from tris(dibenzylideneacetone)dipalladium and Xantphos.

see article for more examples



Key Words

phosphine oxides, phosphonates


ID: J54-Y2012-2820