A Multipathway Coupled Domino Strategy: Metal-free Oxidative Cyclization for One-Pot Synthesis of 2-Acylbenzothiazoles from Multiform Substrates
Yan-ping Zhu, Feng-cheng Jia, Mei-cai Liu and An-xin Wu*
*Key Laboratory of Pesticide & Chemical Biology, Ministry of
Education, College of Chemistry, Central China Normal University, Hubei, Wuhan
430079, P. R. China, Email: chwuax
mail.ccnu.edu.cn
Y.-p. Zhu, F.-c. Jia, M.-c. Liu, A.-x. Wu, Org. Lett., 2012, 14, 4414-4417.
DOI: 10.1021/ol301921t
see article for more reactions
Abstract
A multipathway coupled oxidation/heterocyclization domino strategy enables an efficient synthesis of 2-acylbenzothiazoles from various substrates including arylethenes, arylacetylenes, 2-hydroxy-aromatic ketones and carbinols via four distinct pathways free of metal in one pot.
see article for more examples
Key Words
ID: J54-Y2012-2840
