Palladium-Catalyzed Synthesis of 2,3,4-Trisubstituted Furans via Cascade Reactions of Aryloxy-enynes with Aryl Halides
Ende Li, Xingcan Cheng, Chengyu Wang, Yushang Shao and Yanzhong Li*
*Department of Chemistry, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People’s Republic of China, Email: yzlichem.ecnu.edu.cn
E. Li, X. Cheng, C. Wang, Y. Shao, Y. Li, J. Org. Chem., 2012, 77, 7744-7748.
DOI: 10.1021/jo3012545 (free Supporting Information)
A highly efficient palladium-catalyzed cascade reaction of aryloxy-enynes with aryl halides under mild reaction conditions offers rapid access to 2,3,4-trisubstituted furans in very good yields in a regioselective manner.
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