Palladium-Catalyzed One-Pot Cross-Coupling of Phenols Using Nonafluorobutanesulfonyl Fluoride
Takashi Ikawa, Kozumo Saito, Shuji Akai*
*School of Pharmaceutical Sciences, University of Shizuoka, Yada, Suruga-ku, Shizuoka, Shizuoka 422-8526, Japan, Email: akaiu-shizuoka-ken.ac.jp
T. Ikawa, K. Saito, S. Akai, Synlett, 2012, 23, 2241-2246.
DOI: 10.1055/s-0032-1317076
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Abstract
In situ nonaflation of phenols using nonafluorobutanesulfonyl fluoride (NfF) enables Palladium-catalyzed coupling reactions, such as the Suzuki-Miyaura, Sonogashira, Stille, and Buchwald-Hartwig couplings.
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Key Words
phenols, cross-coupling, Suzuki coupling, palladium, boronic acids, biaryls, nonaflate
ID: J60-Y2012-3040