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Heck Reaction of Baylis-Hillman Adducts with Iodobenzenes Using a Catalytic Amount of Pd/C under Solvent-Free Conditions

Hyun-Soo Kim, Sang-Jin Lee, Boram Choi, Cheol Min Yoon*

*Department of Advanced Material Chemistry, Korea University, Jochiwon, Choongnam 339-770, South Korea, Email:

H.-S. Kim, S.-J. Lee, B. Choi, C. M. Yoon, Synthesis, 2012, 44, 3161-3164.

DOI: 10.1055/s-0032-1316992


Very efficient reactions of Baylis-Hillman adducts with iodobenzenes using commercially available palladium-on-carbon as a catalyst under solvent-free conditions afforded α-benzyl-β-keto esters in very good yields.

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Key Words

palladium on carbon, Heck reaction, arylation, Baylis-Hillman adducts, α-benzyl-β-keto ester

ID: J66-Y2012-3330