Pd-Catalyzed Cascade Reaction for the Synthesis of 2-Substituted Indoles
Jagannath Jadhav, Vipul Gaikwad, Rajanikant Kurane, Rajashri Salunkhe, Gajanan Rashinkar*
*Department of Chemistry, Shivaji University, Kolhapur 416004, M.S., India, Email: gsr_chemunishivaji.ac.in
J. Jadhav, V. Gaikwad, R. Kurane, R. Salunkhe, G. Rahsinkar, Synlett, 2012, 23, 2511-2515.
An efficient cascade methodology toward the synthesis of 2-substituted indoles proceeds via a palladium-catalyzed cross-coupling reaction of o-nitrobenzyl cyanides with boronic acids in the presence of Fe as co-catalyst.
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cascade synthesis, 2-substituted indoles, palladium-catalyzed cross-coupling reaction