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Fe-Catalyzed One-Pot Synthesis of 1,3-Di- and 1,3,5-Trisubstituted Pyrazoles from Hydrazones and Vicinal Diols

Niranjan Panda* and Ashis Kumar Jena

*Department of Chemistry, National Institute of Technology, Rourkela-769008 Odisha, India, Email:

N. Panda, A. K. Jena, J. Org. Chem., 2012, 77, 9401-9406.

DOI: 10.1021/jo301770k

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An iron-catalyzed route for the regioselective synthesis of 1,3- and 1,3,5-substituted pyrazoles from the reaction of diarylhydrazones and vicinal diols allows the conversions of a broad range of substrates.

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Key Words

Pyrazoles, TBHP, Oxygen

ID: J42-Y2012-3410