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Iodine-Mediated Intramolecular Electrophilic Aromatic Cyclization in Allylamines: A General Route to Synthesis of Quinolines, Pyrazolo[4,3-b]pyridines, and Thieno[3,2-b]pyridines

Harikrishna Batchu, Soumya Bhattacharyya and Sanjay Batra*

*Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, PO Box 173, Lucknow 226001, India, Email:

H. Batchu, S. Bhattacharyya, S. Batra, Org. Lett., 2012, 14, 6330-6333.

DOI: 10.1021/ol303109m

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An unprecedented synthesis of aromatic ring annulated pyridines from suitably substituted primary allylamines via intramolecular electrophilic aromatic cyclization is mediated by molecular iodine under mild conditions.

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Key Words


ID: J54-Y2012-3920