Ni-Catalyzed Direct Carboxylation of Benzyl Halides with CO₂

Thierry León, Arkaitz Correa and Ruben Martin*

*Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona, Spain, Email: rmartinromoiciq.es

T. León, A. Correa, R. Martin, J. Am. Chem. Soc., 2013, 135, 1221-1224.

DOI: 10.1021/ja311045f

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Abstract

A Ni-catalyzed carboxylation of benzyl halides with CO₂ proceeds under mild conditions at room temperature under atmospheric pressure. The method does not require well-defined and sensitive organometallic reagents and thus is user-friendly and operationally simple.

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Ni-Catalyzed Carboxylation of Unactivated Alkyl Chlorides with CO₂

M. Börjesson, T. Moragas, R. Martin, J. Am. Chem. Soc., 2016, 138, 7504-7507.

Ni-Catalyzed Carboxylation of Unactivated Primary Alkyl Bromides and Sulfonates with CO₂

Y. Liu, J. Cornella, R. Martin, J. Am. Chem. Soc., 2014, 136, 11212-11215.

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Key Words

carboxylation, benzylation, Zn

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ID: J48-Y2013-0130