Pd-Catalyzed P-C Cross-Coupling Reactions for Versatile Triarylphosphine Synthesis
Minoru Hayashi*, Takashi Matsuura, Ippei Tanaka , Hidetoshi Ohta and Yutaka Watanabe
*Department of Materials Science and Biotechnology, Graduate
School of Science and Engineering, Ehime University, 3 Bunkyo-cho, Matsuyama
790-8577, Japan, Email: mhayashi
ehime-u.ac.jp
M. Hayashi, T. Matsuura, I. Tanaka, H. Ohta, Y. Watanabe, Org. Lett., 2013, 15, 628-631.
DOI: 10.1021/ol303448j
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Abstract
A palladium-catalyzed deformylative P-C cross-coupling reactions of hydroxymethylphosphine derivatives enables a practical and versatile syntheses of tertiary phosphine derivatives. Sequential couplings of orthogonally protected precursors provide a simple and practical route toward a variety of tertiary aryl-substituted phosphine derivatives in any combination.
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Key Words
ID: J54-Y2013-0350
