Catalytic Asymmetric Synthesis of Cyclic Sulfamides from Conjugated Dienes
Richard G. Cornwall, Baoguo Zhao and Yian Shi*
*Department of Chemistry, Colorado State University, Fort
Collins, Colorado 80523, Email: yian
lamar.colostate.edu
R. G. Cornwall, B. Zhao, Y. Shi, Org. Lett., 2013, 15, 796-799.
DOI: 10.1021/ol303469a
Abstract
A catalytic asymmetric diamination of alkyl dienes using N,N′-di-tert-butylthiadiaziridine 1,1-dioxide in the presence of Pd(0) and a chiral phosphoramidite ligand gives cyclic sulfamides in high yield and high ee. The diamination is also amenable to gram scale.
see article for more examples
Diamination of Conjugated Dienes and Trienes Catalyzed by N-Heterocyclic Carbene-Pd(0) Complexes
L. Xu, H. Du, Y. Shi, J. Org. Chem., 2007, 72, 7038-7041.
Key Words
ID: J54-Y2013-0420
