Cu(OAc)2-Catalyzed Thiolation of Acyl C-H Bonds with Thiols Using TBHP as an Oxidant
Yan-qin Yuan*, Sheng-rong Guo, Jian-nan Xiang*
*Department of Chemistry, Lishui University, 323000 Lishui
and College of Chemistry and Chemical Engineering, Hunan University, Changsha
410082, P. R. of China, Email: guosr9609
lsu.edu.cn, jnxianghnu.edu.cn
Y.-q. Yuan, S.-r. Guo, J.-n. Xiang, Synlett, 2013, 24, 443-448.
DOI: 10.1055/s-0032-1318188
Abstract
Cu(OAc)2-promoted TBHP oxidative coupling reaction of formamides with thiophenols gives S-aryl dialkyl thiocarbamates in high yield under solvent-free conditions through direct C-H bond activation of formamides.
see article for more examples
Key Words
TBHP, Cu(OAc)2, thiolation, thiols, formamides
ID: J60-Y2013-0490
