Tin(IV) Chloride Promoted Reaction of Oxiranes with Hydrogen Peroxide
Xing Yan, Chunhua Qiao*, Zhongwu Guo
*College of Pharmaceutical Science, Soochow University, 199 Ren Ai Road, Suzhou 215123, P. R. of China, Email: qiaochunhuasuda.edu.cn
X. Yan, C. Qiao, Z. Guo, Synlett, 2013, 24, 502-506.
see article for more reactions
Substituted oxiranes were readily transformed to the corresponding β-hydroxyhydroperoxides in good yields in ethereal H2O2 system with SnCl4 as a catalyst. Alternatively, the use of a stoichiometric amount of SnCl4 leads to a rearrangement of the oxiranes to aldehydes. A subsequent addition of ethereal H2O2 solution achieves primary gem-dihydroperoxides in moderate yields.
see article for more examples
SnCl4, oxiranes, β-hydroxyhydroperoxides, gem-dihydroperoxides, peroxides