Mild Copper-Mediated Fluorination of Aryl Stannanes and Aryl Trifluoroborates
Yingda Ye and Melanie S. Sanford*
*Department of Chemistry, University of Michigan, 930 North
University Avenue, Ann Arbor, Michigan 48109, United States, Email:
mssanfor
umich.edu
Y. Ye, M. S. Sanford, J. Am. Chem. Soc., 2013, 135, 4648-4651.
DOI: 10.1021/ja400300g
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Abstract
A mild copper-mediated fluorination of aryl stannanes and aryl trifluoroborates with N-fluoro-2,4,6-trimethylpyridinium triflate (NFTPT) demonstrates broad substrate scope and functional group tolerance, and does not require the use of any noble metal additives. The reaction is proposed to proceed via an arylcopper(III) fluoride intermediate.
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Key Words
ID: J48-Y2013-0680
