Regio- and Stereoselective Hydrosilylation of 1,3-Enynes Catalyzed by Palladium

Hui Zhou and Christina Moberg*

*Department of Chemistry, Organic Chemistry, School of Chemical Science and Engineering, KTH Royal Institute of Technology, SE 100 44 Stockholm, Sweden, Email: kimokth.se

H. Zhou, C. Moberg, Org. Lett., 2013, 15, 1444-1447.

DOI: 10.1021/ol4001334

---

see article for more reactions

Abstract

In the presence of Pd(0) and a phosphine, a hydrosilylation of 1,3-enynes with Me₂SiHCl yields dienylsilanes with (E)-configuration and with the silicon group added to the internal alkyne carbon atom. Subsequent hydrolysis gives silanols, that serve as precursors to conjugated dienes with different substitution patterns.

see article for more examples

---

---

Key Words

Vinylsilanoles, Vinylsilanes

---

ID: J54-Y2013-0820