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L-Proline: An Efficient Catalyst for Transamidation of Carboxamides with Amines

Sadu Nageswara Rao, Darapaneni Chandra Mohan and Subbarayappa Adimurthy*

*CSIR-Central Salt & Marine Chemicals Research Institute, G. B. Marg, Bhavnagar-364 002, Gujarat, India, Email:

S. N. Rao, D. C. Mohan, S. Admurthy, Org. Lett., 2013, 15, 1496-1499.

DOI: 10.1021/ol4002625


In the presence of a catalytic amount of L-proline, transamidations of carboxamides with amines were achieved under solvent-free conditions. The reaction tolerates a wide range of amines.

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ID: J54-Y2013-0870