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A Practical Synthesis of Azobenzenes through Oxidative Dimerization of Aromatic Amines Using tert-Butyl Hypoiodite

Youhei Takeda, Sota Okumura, Satoshi Minakata*

*Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan, Email:

Y. Takeda, S. Okumura, S. Minakata, Synthesis, 2013, 45, 1029-1033.

DOI: 10.1055/s-0032-1318388


A straightforward, convenient, and efficient oxidative dimerization of aromatic amines enables an easy access to symmetrical and unsymmetrical azobenzenes under extremely mild conditions using a unique and cost-effective iodinating reagent.

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Key Words

amines, azo compounds, dimerization, oxidation, tert-butyl hypochlorite

ID: J66-Y2013-0960