N-Indolyltriethylborate: A Useful Reagent for Synthesis of C3-Quaternary Indolenines
Aijun Lin, Jiong Yang* and Mohamed Hashim
*Department of Chemistry, Texas A&M University, College Station, Texas 77843-3255, United States, Email: yangmail.chem.tamu.edu
A. Lin, J. Yang, M. Hashim, Org. Lett., 2013, 15, 1950-1953.
DOI: 10.1021/ol4005992 (free Supporting Information)
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N-Indolyltriethylborate is a useful reagent for dearomatizing C3-alkylation of 3-substituted indoles with both activated and nonactivated alkyl halides to give C3-quaternary indolenines, pyrroloindolines, furoindoline, and hexahydropyridoindoline under mild reaction conditions.
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