P-Arylation: Arynes to Aryl-Phosphonates, -Phosphinates, and -Phosphine Oxides
Ranjeet A. Dhokale and Santosh B. Mhaske*
*Division of Organic Chemistry, National Chemical Laboratory (CSIR-NCL), Pune 411008, India, Email: sb.mhaskencl.res.in
R. A. Dhokale, S. B. Mhaske, Org. Lett., 2013, 15, 2218-2221.
DOI: 10.1021/ol400780f (free Supporting Information)
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An efficient use of arynes for C-P bond construction enables a mild process for the synthesis of aryl-phosphonates, -phosphinates, and -phosphine oxides. The reaction circumvents the relatively harsh reaction conditions using transition-metal-catalyzed P-arylation (Arbuzov/Hirao reaction).
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