Fast and Efficient Bromination of Aromatic Compounds with Ammonium Bromide and Oxone
Mameda Naresh, Macharla Arun Kumar, Marri Mahender Reddy, Peraka Swamy, Jagadeesh Babu Nanubolu, Nama Narender*
*I&PC Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India, Email: narendern33yahoo.co.in
N. Naresh, M. A. Kumar, M. M. Reddy, P. Swamy, J. B. Nanubolu, N. Narender, Synthesis, 2013, 45, 1497-1504.
DOI: 10.1055/s-0033-1338431 (free Supporting Information)
A highly efficient, rapid and regioselective protocol for the ring bromination of aromatic compounds under mild conditions can be conducted with ammonium bromide as a source of bromine source and Oxone as an oxidant. Various aromatic compounds reacted smoothly to give the corresponding monobrominated products in good yields in very short reaction times.
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M. A. Kumar, C. N. Rohitha, S. J. Kulkarni, N. Narender, Synthesis, 2010, 1629-1632.