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Iron-Catalyzed Direct Synthesis of Imines from Amines or Alcohols and Amines via Aerobic Oxidative Reactions under Air

Erlei Zhang, Haiwen Tian, Sendong Xu, Xiaochun Yu and Qing Xu*

*College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035, China, Email:

E. Zhang, H. Tian, S. Xu, X. Yu, Q. Xu, Org. Lett., 2013, 15, 2704-2707.

DOI: 10.1021/ol4010118

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Iron-catalyzed aerobic oxidative reactions of primary amines, secondary amines, benzylamines with anilines, and alcohols with amines in the presence of air as the economic and safe oxidant, provide several direct, practical, and greener approaches for the preparation of useful imines.

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Key Words

imines, oxygen, TEMPO

ID: J54-Y2013