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A New Strategy for the Construction of α-Amino Acid Esters via Decarboxylation

Jie Zhang, Jiewen Jiang, Yuling Li, Yun Zhao and Xiaobing Wan*

*Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China, Email:

J. Zhang, J. Jiang, Y. Li, Y. Zhao, X. Wang, Org. Lett., 2013, 15, 3222-3225.

DOI: 10.1021/ol401139m

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A new α-amino acid esters formation via decarboxylation is distinguished by readily accessible starting materials, environmentally benign reaction conditions and waste streams, and wide substrate scope.

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Key Words

α-amino esters, tert-butyl hydroperoxide

ID: J54-Y2013