Organic Chemistry Portal

Abstracts

Search:

A New Strategy for the Construction of α-Amino Acid Esters via Decarboxylation

Jie Zhang, Jiewen Jiang, Yuling Li, Yun Zhao and Xiaobing Wan*

*Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China, Email: wanxbsuda.edu.cn

J. Zhang, J. Jiang, Y. Li, Y. Zhao, X. Wang, Org. Lett., 2013, 15, 3222-3225.

DOI: 10.1021/ol401139m (free Supporting Information)


see article for more reactions

Abstract

A new α-amino acid esters formation via decarboxylation is distinguished by readily accessible starting materials, environmentally benign reaction conditions and waste streams, and wide substrate scope.


see article for more examples



Key Words

α-amino esters, tert-butyl hydroperoxide


ID: J54-Y2013