A Room-Temperature Catalytic Asymmetric Synthesis of Allenes with ECNU-Phos
Yuli Wang, Wanli Zhang and Shengming Ma*
*State Key Laboratory of Organometallic Chemistry, Shanghai
Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu,
Shanghai 200032, China, Email: masm
sioc.ac.cn
Y. Wang, W. Zhang, S. Ma, J. Am. Chem. Soc., 2013, 135, 11517-11520.
DOI: 10.1021/ja406135t
Abstract
The combination of [(π-allyl)PdCl]2 with [(R)-ECNU-Phos], a new chiral bisphosphine ligand based on a biphenyl skeleton, demonstrates high enantioselectivity in a catalytic asymmetric carbonylation of readily available racemic propargylic carbonates to access optically active 2,3-allenoates.
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Key Words
α,β-unsaturated esters, allenes
ID: J48-Y2013
