Copper(I) Iodide Catalyzed Synthesis of Thiophosphates by Coupling of H-Phosphonates with Benzenethiols
Babak Kaboudin*, Yaghoub Abedi, Jun-ya Kato, Tsutomu Yokomatsu
*Department of Chemistry, Institute for Advanced Studies in
Basic Sciences (IASBS), Zanjan 45137-66731, Iran, Email: kaboudin
iasbs.ac.ir
B. Kaboudin, Y. Abedi, J.-Y. Kato, T. Yokomatsu, Synthesis, 2013, 45, 2323-2327.
Abstract
A simple and efficient method for the preparation of thiophosphates from benzenethiols involves copper(I) iodide catalyzed coupling of thiols with H-phosphonates in the presence of triethylamine. The reaction proceeds effectively via an aerobic dehydrogenative coupling to afford the corresponding thiophosphates in good yields.
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Key Words
phosphorothioates, copper iodide, thiols, H-phosphonates, coupling, oxygen
ID: J66-Y2013
