Palladium-Catalyzed Methylation of Alkynyl C(sp)-H Bonds with Dimethyl Sulfonium Ylides
Yan-Yun Liu, Xu-Heng Yang, Xiao-Cheng Huang, Wen-Ting Wei, Ren-Jie Song and Jin-Heng Li*
*State Key Laboratory of Chemo/Biosensing and Chemometrics,
College of Chemistry and Chemical Engineering, Hunan University, Changsha
410082, China, Email: jhli
hnu.edu.cn
Y.-Y. Liu, X.-H. Yang, X.-C. Huang, W.-T. Wei, R.-J. Song, J.-H. Li, J. Org. Chem., 2013, 78, 10421-10426.
DOI: 10.1021/jo401851m
Abstract
Sulfonium ylides can be used as alkyl electrophiles in a palladium-catalyzed methylation protocol for the synthesis of methyl-functionalized internal alkynes via a C(sp)-C(sp3) bond formation process.
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Key Words
ID: J42-Y2013
