Conversion of Pyridine to Imidazo[1,2-a]pyridines by Copper-Catalyzed Aerobic Dehydrogenative Cyclization with Oxime Esters
Huawen Huang, Xiaochen Ji, Xiaodong Tang, Min Zhang, Xianwei Li and Huanfeng Jiang*
*School of Chemistry and Chemical Engineering, South China
University of Technology, Guangzhou 510640, P. R. China, Email: jianghf
scut.edu.cn
H. Huang, X. Ji, X. Tang, M. Zhang, X. Li, H. Jiang, Org. Lett., 2013, 15, 6254-6257.
DOI: 10.1021/ol403105p
see article for more reactions
Abstract
A rapid, copper-catalyzed aerobic dehydrogenative cyclization of pyridines with ketone oxime esters enables an environmentally friendly synthesis of imidazo[1,2-a]pyridines.
see article for more examples
Key Words
imidazo[1,2-a]pyridines, oxygen
ID: J54-Y2013
