Palladium-Catalyzed α-Arylation of Benzylic Phosphine Oxides
Sonia Montel, Tiezheng Jia and Patrick J. Walsh*
*Department of Chemistry, University of Pennsylvania, 231
South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States, Email:
pwalsh
sas.upenn.edu
S. Montel, T. Jia, P. J. Walsh, Org. Lett., 2014, 16, 130-133.
DOI: 10.1021/ol403124g
Abstract
A Pd(OAc)2/Xantphos-based catalyst enabled a deprotonative cross-coupling process between benzyl diphenyl or dicyclohexyl phosphine oxide derivatives and aryl bromides to prepare diarylmethyl phosphine oxides in very good yields.
see article for more examples
Palladium-Catalyzed α-Arylation of Benzylic Phosphonates
S. Montel, L. Raffier, Y. He, P. J. Walsh, Org. Lett., 2014, 16, 1446-1449.
Palladium-Catalyzed Direct Arylation of Methyl Sulfoxides with Aryl Halides
T. Jia, A. Bellomo, K. El Baina, S. D. Dreher, P. J. Walsh, J. Am. Chem. Soc., 2013, 135, 3740-3743.
Key Words
ID: J54-Y2014
