Simple Synthesis of 2-Aminoaryliminophosphoranes from N-Aryl-2-nitrosoanilines and Their Application in 2-Aminobenzimidazole Synthesis
Emilia Łukasik, Zbigniew Wróbel*
*Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44, 01-224 Warsaw, Poland, Email: zbigniew.wrobelicho.edu.pl
E. Łukasik, Z. Wróbel, Synlett, 2014, 25, 217-220.
DOI: 10.1055/s-0033-1340055
Abstract
Condensation of N-aryl-2-nitrosoanilines with triphenylphosphine gives substituted aryliminophosphoranes which in a subsequent reaction with alkyl isocyanates furnish 2-alkylaminobenzimidazole derivatives in high yields.
see article for more examples
M. Walewska-Królikiewicz, B. Wilk, A. Kwast, Z. Wróbel, Synlett, 2022, 33, 1092-1096.
Key Words
cyclization, condensation, heterocycles, annulation, benzimidazoles
ID: J60-Y2014