Benzoquinone-Promoted Aerobic Oxidative Hydroxylation of Arylboronic Acids in Water
Guolin Cheng, Xiaobao Zeng, Xiuling Cui*
*Institute of Molecular Medicine and School of Biomedical
Sciences, Huaqiao University, Xiamen 361021, P. R. of China, Email: cuixl
hqu.edu.cn
G. Chen, X. Zeng, X. Cui, Synthesis, 2014, 46, 263-268.
DOI: 10.1055/s-0033-1338571
Abstract
A general and efficient aerobic oxidative hydroxylation of arylboronic acids promoted by benzoquinone provides phenols in very good yields. The main advantages of this protocol are the use of water as solvent in the presence of a catalytic amount of benzoquinone under metal-free conditions.
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Key Words
benzoquinone, arylboronic acids, oxidation, oxygen, phenols
ID: J66-Y2014
