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Erbium Triflate Promoted Multicomponent Synthesis of Highly Substituted Imidazoles

Kandasamy Rajaguru, Rajendran Suresh, Arumugam Mariappan, Shanmugam Muthusubramanian* and Nattamai Bhuvanesh

*Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India, Email:

K. Rajaguru, R. Suresh, A. Mariappan, S. Muthusubramanian, N. Bhuvanesh, Org. Lett., 2014, 16, 744-747.

DOI: 10.1021/ol403456b

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A multicomponent protocol enables the synthesis of highly substituted imidazole derivatives in excellent yield from various α-azido chalcones, aryl aldehydes, and anilines in the presence of erbium triflate as a catalyst.

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Key Words

imidazoles, multicomponent reactions

ID: J54-Y2014