NIS-Mediated Oxidative Lactonization of 2-Arylbenzoic Acids for the Synthesis of Dibenzopyranones under Metal-Free Conditions
Peng Gao, Yunyang Wei*
*School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. of China, Email: yweimail.njust.edu.cn
P. Gao, Y. Wei, Synthesis, 2014, 46, 343-347.
DOI: 10.1055/s-0033-1338568 (free Supporting Information)
A convenient radical oxidative cyclization mediated by N-iodosuccinimide (NIS) enables the synthesis of a series of dibenzopyranones from a wide scope of 2-arylbenzoic acids. The methodology offers good functional group tolerance and mild reaction conditions without the use of transition metals.
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