Aldehydes and Ketones Formation: Copper-Catalyzed Aerobic Oxidative Decarboxylation of Phenylacetic Acids and α-Hydroxyphenylacetic Acids
Qiang Feng and Qiuling Song*
*Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University, Xiamen, Fujian, 361021, China, Email: qsonghqu.edu.cn
Q. Feng, Q. Song, J. Org. Chem., 2014, 79, 1867-1871.
DOI: 10.1021/jo402778p (free Supporting Information)
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A copper-catalyzed aerobic oxidative decarboxylation of phenylacetic acids and α-hydroxyphenylacetic acids enables the synthesis aromatic carbonyl compounds via decarboxylation, dioxygen activation, and C-H bond oxidation steps in a one-pot protocol with molecular oxygen as the sole terminal oxidant.
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