Copper-Catalyzed N-Arylation of Sulfonamides with Boronic Acids in Water under Ligand-Free and Aerobic Conditions
Mahmoud Nasrollahzadeh*, Ali Ehsani, Mehdi Maham
*Department of Chemistry, Faculty of Science, University of
Qom, PO Box 3716146611, Qom, Iran, Email: mahmoudnasr81gmail.com
M. Nasrollahzadeh, A. Ehsani, M. Maham, Synlett, 2014, 25, 505-508.
DOI: 10.1055/s-0033-1340475
see article for more reactions
Abstract
An efficient method for the copper-catalyzed arylation of sulfonamides in water under ligand-free conditions offers high yields, simple workup procedure, and elimination of toxic materials.
see article for more examples
Key Words
Chan-Lam coupling, arylation, ligand-free, copper, boronic acids, sulfonamides, water, green chemistry
ID: J60-Y2014