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Palladium-Catalyzed Intramolecular Hydroamination of Propargylic Carbamates and Carbamothioates

Santosh Kumar Alamsetti, Andreas K. Å. Persson and Jan-E. Bäckvall*

*Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm, Sweden, Email:

S. K. Alamsetti, A. K. Å. Persson, J.-E. Bäckvall, Org. Lett., 2014, 16, 1434-1437.

DOI: 10.1021/ol5002279 (free Supporting Information)

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The use of Pd(OAc)2 and n-Bu4NOAc as catalysts enables an efficient and simple synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials in DCE at room temperature.

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Key Words


ID: J54-Y2014