Organic Chemistry Portal

Abstracts

Search:

Palladium-Catalyzed Intramolecular Hydroamination of Propargylic Carbamates and Carbamothioates

Santosh Kumar Alamsetti, Andreas K. Å. Persson and Jan-E. Bäckvall*

*Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm, Sweden, Email: jeborgan.su.se

S. K. Alamsetti, A. K. Å. Persson, J.-E. Bäckvall, Org. Lett., 2014, 16, 1434-1437.

DOI: 10.1021/ol5002279 (free Supporting Information)


see article for more reactions

Abstract

The use of Pd(OAc)2 and n-Bu4NOAc as catalysts enables an efficient and simple synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials in DCE at room temperature.

see article for more examples



Key Words

oxazolidinones


ID: J54-Y2014