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C-H Activation of Methyl Arenes in the MnO2-Mediated Aroylation of N-Chlorosulfoximines

Daniel L. Priebbenow and Carsten Bolm*

*Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany, Email:

D. L. Priebbenow, C. Bolm, Org. Lett., 2014, 16, 1650-1652.

DOI: 10.1021/ol5003016 (free Supporting Information)


A method for the synthesis of N-aroylated sulfoximines involves a manganese oxide promoted C-H activation of methyl arenes to form an aroyl intermediate which then reacts readily with N-chlorosulfoximines to form a series of valuable aroyl sulfoximine derivatives in high yields.

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Key Words

sulfoximines, MnO2, TBHP, NCS

ID: J54-Y2014