Facile Synthesis of Z-Alkenes via Uphill Catalysis
Kamaljeet Singh, Shannon J. Staig and Jimmie D. Weaver*
*Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States, Email: Jimmie.weaverokstate.edu
K. Singh, S. J. Staig, J. D. Weaver, J. Am. Chem. Soc., 2014, 136, 5275-5278.
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Catalytic access to thermodynamically less stable Z-alkenes have relied upon kinetic control of the reaction. A mild and simple orthogonal approach proceeds via photochemically catalyzed isomerization of the thermodynamic E-alkene to the less stable Z-isomer via a photochemical pumping mechanism.
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isomerizations, Z-alkenes, allylic amines, allylic alcohols