Palladium-Catalyzed Decarboxylative Trifluoroethylation of Aryl Alkynyl Carboxylic Acids
Jinil Hwang, Kyungho Park, Juseok Choe, Hongkeun Min, Kwang Ho Song* and Sunwoo Lee*
*Department of Chemical & Biological Engineering, Korea University, Seoul 136-713; Department of Chemistry, Chonnam National University, Gwangju 500-757, Republic of Korea, Email: khsongkorea.ac.kr, sunwoochonnam.ac.kr
J. Hwang, K. Park, J. Choe, H. Min, K. H. Song, S. Lee, J. Org. Chem., 2014, 79, 3267-3271.
DOI: 10.1021/jo5003032 (free Supporting Information)
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A palladium-catalyzed decarboxylative coupling reaction of aryl alkynyl carboxylic acids and ICH2CF3 enables a trifluoroethylation of alkynes in good yields. The catalytic system showed high functional group tolerance.
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