Chemoselective Palladium-Catalyzed Cyanation of Alkenyl Halides
Kimberley J. Powell, Li-Chen Han, Pallavi Sharma and John E. Moses*
*School of Chemistry, University of Nottingham, University
Park, Nottingham, NG7 2RD, U.K., Email:
john.moses
nottingham.ac.uk
K. J. Powell, L-C. Han, P. Sharma, J. E. Moses, Org. Lett., 2014, 16, 2158-2161.
DOI: 10.1021/ol500618w
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Abstract
A palladium-catalyzed cyanation of alkenyl halides using acetone cyanohydrin enables the preparation of structurally diverse alkenylic nitrile containing compounds in one step. The reaction is efficient, chemoselective, easy to perform, and tolerates a number of functional groups.
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Key Words
ID: J54-Y2014
