Odourless Strategy for Deep Eutectic Solvent-Mediated Ring Opening of Epoxides with In Situ Generated S-Alkylisothiouronium Salts
Najmedin Azizi*, Zahra Yadollahy, Amin Rahimzadeh-oskooee
*Chemistry & Chemical Engineering Research Center of Iran,
P.O. Box 14335-186, Tehran, Iran, Email: azizi
ccerci.ac.ir
N. Azizi, Z. Yadollahy, A. Rahimzadeh-oskooee, Synlett, 2014, 25, 1085-1088.
DOI: 10.1055/s-0033-1341050
Abstract
A general, straightforward and odourless ring-opening reaction allows the preparation of β-hydroxy sulfides from in situ generated S-alkylisothiouronium salts in urea-choline chloride-based deep eutectic solvent (DES). The reaction of epoxides with thiourea in DES yields the corresponding thiiranes.
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Key Words
deep eutectic solvents, epoxides, thiiranes, sulfides, odourless thiol chemistry
ID: J60-Y2014
