2,2,2-Trifluoroacetophenone: An Organocatalyst for an Environmentally Friendly Epoxidation of Alkenes
Dimitris Limnios and Christoforos G. Kokotos*
*Laboratory of Organic Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis, 15771 Athens, Greece, Email: ckokotoschem.uoa.gr
D. Limniois, C. G. Kokotos, J. Org. Chem., 2014, 79, 4270-4276.
DOI: 10.1021/jo5003938 (free Supporting Information)
2,2,2-trifluoroacetophenone is an efficient organocatalyst for a cheap, mild, fast, and environmentally friendly epoxidation of alkenes. Various olefins, mono-, di-, and trisubstituted, are epoxidized chemoselectively in high to quantitative yields utilizing low catalyst loadings and H2O2 as a green oxidant.
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