A Highly Efficient Cu-Catalyzed S-Transfer Reaction: From Amine to Sulfide
Yiming Li, Jiahua Pu and Xuefeng Jiang*
*Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062, P. R. China, Email: xfjiangchem.ecnu.edu.cn
Y. Li, J. Pu, X. Jiang, Org. Lett., 2014, 16, 2692-2695.
Inodorous stable Na2S2O3 is used as a sulfurating reagent in a Cu-catalyzed dual C-S bonds formation reaction, that proceeds in alcohol and water under air. This powerful strategy provides a practical and efficient approach to construct thioethers, using readily available aromatic amines and alkyl halides as starting materials. Sensitive and synthetic useful functional groups are tolerated.
see article for more examples
aryl sulfides, Sandmeyer Reaction