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Arylboration of Alkenes by Cooperative Palladium/Copper Catalysis

Kazuhiko Semba* and Yoshiaki Nakao*

*Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan, Email:,

K. Semba, Y. Nakao, J. Am. Chem. Soc., 2014, 136, 7567-7570.

DOI: 10.1021/ja5029556

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Arylboration of vinylarenes and methyl crotonate with aryl halides and bis(pinacolato)diboron by cooperative Pd/Cu catalysis gives 2-boryl-1,1-diarylethanes and α-aryl-β-boryl ester in a regioselective manner. The reaction is compatible with various functionalities and can be scaled-up to a gram scale.

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Key Words

Diarylalkanes, Boronates, Multicomponent Reactions

ID: J48-Y2014