Arylboration of Alkenes by Cooperative Palladium/Copper Catalysis
Kazuhiko Semba* and Yoshiaki Nakao*
*Department of Material Chemistry, Graduate School of
Engineering, Kyoto University, Kyoto 615-8510, Japan, Email: semba.kazuhiko.5n
kyoto-u.ac.jp,
nakao.yoshiaki.8nkyoto-u.ac.jp
K. Semba, Y. Nakao, J. Am. Chem. Soc., 2014, 136, 7567-7570.
DOI: 10.1021/ja5029556
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Abstract
Arylboration of vinylarenes and methyl crotonate with aryl halides and bis(pinacolato)diboron by cooperative Pd/Cu catalysis gives 2-boryl-1,1-diarylethanes and α-aryl-β-boryl ester in a regioselective manner. The reaction is compatible with various functionalities and can be scaled-up to a gram scale.
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Key Words
Diarylalkanes, Boronates, Multicomponent Reactions
ID: J48-Y2014
