Enantiospecific Intramolecular Heck Reactions of Secondary Benzylic Ethers
Michael R. Harris, Mikhail O. Konev and Elizabeth R. Jarvo*
*Department of Chemistry, University of California, Irvine,
California 92697-2025, United States, Email: erjarvo
uci.edu
M. R. Harris, M. O. Konev, E. R. Jarvo, J. Am. Chem. Soc., 2014, 136, 7825-7828.
DOI: 10.1021/ja5026485
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Abstract
Stereospecific, nickel-catalyzed Heck cyclizations of secondary benzylic ethers proceeds in high yield and enantiospecificity to yield enantioenriched methylenecyclopentanes for benzylic ethers of both π-extended and simple arenes.
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Key Words
ID: J48-Y2014
