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Ruthenium-Catalyzed Cyclization of Anilides with Substituted Propiolates or Acrylates: An Efficient Route to 2-Quinolinones

Rajendran Manikandan and Masilamani Jeganmohan*

*Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India, Email: mjeganmohaniiserpune.ac.in

R. Manikandan, M. Jeganmohan, Org. Lett., 2014, 16, 3568-3571.

DOI: 10.1021/ol501548e (free Supporting Information)


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Abstract

A Ru-catalyzed cyclization of anilides with propiolates or acrylates affords 2-quinolones having diverse functional groups in good to excellent yields. 2-quinolinones can be converted into 3-halo-2-quinolinones and 2-chloroquinolines.

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Key Words

2-quinolones


ID: J54-Y2014