Cu-Catalyzed Arylcarbocyclization of Alkynes with Diaryliodonium Salts through C-C Bond Formation on Inert C(sp3)-H Bond
Jing Peng, Chao Chen*, Junjie Chen, Xiang Su, Chanjuan Xi and Hui Chen*
*Department of Chemistry, Tsinghua University, Beijing 100084; Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China, Email: chenchao01mails.tsinghua.edu.cn, chenhiccas.ac.cn
J. Peng, C. Chen, J. Chen, X. Su, C. Xi, H. Chen, Org. Lett., 2014, 16, 3776-3779.
DOI: 10.1021/ol501655g (free Supporting Information)
Copper-catalyzed arylcarbocyclization of alkynes with diaryliodonium salts provides carbocycles with good step-economy through C-C bond formation on an inert C(sp3)-H bond. Theoretical studies revealed an interesting Cu-catalyzed concerted pathway of the C-C bond formation.
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