Rational Design of a Second Generation Catalyst for Preparation of Allylsilanes Using the Silyl-Heck Reaction
Jesse R. McAtee, Glenn P. A. Yap and Donald A. Watson*
*Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States, Email: dawatsonudel.edu
J. R. McAtee, G. P. A. Yap, D. A. Watson, J. Am. Chem. Soc., 2014, 136, 10166-10172.
DOI: 10.1021/ja505446y
Abstract
A second-generation ligand, bis(3,5-di-tert-butylphenyl)(tert-butyl)phosphine, enables the preparation of allylsilanes using the palladium-catalyzed silyl-Heck reaction. This ligand provides nearly complete suppression of starting material alkene isomerization.
see article for more examples
Key Words
ID: J48-Y2014