Organic Chemistry Portal



Transition-Metal-Free C-S Bond Formation: A Facile Access to Aryl Sulfones from Sodium Sulfinates via Arynes

Virat G. Pandya and Santosh B. Mhaske*

*CSIR-National Chemical Laboratory, Division of Organic Chemistry, Pune 411 008, India, Email:

V. G. Pandya, S. B. Mhaske, Org. Lett., 2014, 16, 3836-3839.

DOI: 10.1021/ol5018646


In an efficient transition-metal-free synthesis of sulfones, a broad range of alkyl/aryl/heteroaryl sodium sulfinates react with varyingly substituted o-silyl aryl triflates as aryne precursors under mild reaction conditions to afford structurally diverse sulfones in good to excellent yields.

see article for more examples

Key Words

aryl sulfones

ID: J54-Y2014