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Efficient Synthesis of Polysubstituted Olefins Using Stable Palladium Nanocatalyst: Applications in Synthesis of Tamoxifen and Isocombretastatin A4

Dhandapani Ganapathy and Govindasamy Sekar*

*Department of Chemistry, Indian Institute of Technology Madras, Chennai, Tamil Nadu 600036, India, Email:

D. Ganapathy, G. Sekar, Org. Lett., 2014, 16, 3856-3859.

DOI: 10.1021/ol5017367  (free Supporting Information)

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A stable palladium nanocatalyst was used for an efficient synthesis of polysubstituted olefins from N-tosylhydrazones and aryl iodides. The nanocatalyst can easily be recovered and reused without any apparent loss in size and catalytic activity.

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ID: J54-Y2014