Photoredox-Induced Three-Component Azido- and Aminotrifluoromethylation of Alkenes
Guillaume Dagousset, Aude Carboni, Emmanuel Magnier* and Géraldine Masson*
*Institut Lavoisier de Versailles, Université de
Versailles-Saint-Quentin, 78035 Versailles Cedex; CNRS, 91198 Gif-sur-Yvette
Cedex, France, Email: emmanuel.magnier
uvsq.fr,
geraldine.massoncnrs.fr
G. Dagousset, A. Carboni, E. Magnier, G. Masson, Org. Lett., 2014, 16, 4340-4343.
DOI: 10.1021/ol5021477
see article for more reactions
Abstract
A photoredox-catalyzed azidotrifluoromethylation of substituted styrenes as well as various activated and nonactivated alkenes using [Ru(bpy)3(PF6)2] as the photocatalyst and Umemoto's reagent as the CF3 source delivers a wide range β-trifluoromethylated azides or amines in good yields.
see article for more examples
Key Words
benzyl azides, alkyl azides, trifluoromethyl alkanes, photochemistry
ID: J54-Y2014
